PRE-GESTATIONAL OBESITY AS A RISK
FACTOR FOR PREECLAMPSIA
Zoila Moreno1, Sixto Sánchez1, Fernando Piña2, Antonia
Reyes1,
Michele Williams3
SUMMARY
OBJECTIVE: To evaluate obesity as a risk factor for preeclampsia. DESIGN: Case-control
study carried out at Dos de Mayo Hospital, Lima, Peru.
MATERIAL AND METHODS: Excluding 35 women, 107 preeclamptic women were compared with 107
normotensive pregnant women (control group) and matched for gestational age (±1 week).
Chi square test was used to correlate the presence of preeclampsia with pre gestational
weight; T test was used to compare means, and logistic regression to adjust for
confounders. RESULTS: Preeclampsia was significantly associated to women aged 35 or older
(OR 3,0; CI 95 1,2 to 7,9), history of a previous pregnancy complicated with preeclampsia
(OR 8,6; CI 95% 1,0 to 76,9), and obesity (OR 6,5; 6,2 to 2,8) considered as women in the
highest tercil of the parameters body mass index (BMI), tricipital skin folding, and mid
arm circunference. There was a significant linear trend (p< 0,001) in preeclampsia risk
with these parameters. CONCLUSION: Women whose weight is in the upper third tercile of
body mass index should be carefully controlled to reduce the incidence of preeclampsia and
its complications.
Key words: Preeclampsia; risk factors; body mass index; obesity;
pre-eclampsia; pregnancy complications.
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